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36 | Central Laboratory Life Sciences

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Life Sciences

Contract fermentation Custom bioprocessing Diagnostic enzymes

EKF Life Sciences has been producing quality diagnostic enzymes and contracted bio-products for more than 20 years.

EKF Life Sciences customers include some of the world leaders in medical diagnostics.

EKF Life Sciences downstream processing applications are designed to address a multitude of client applications. We work to customer specifications to produce a cell paste through various intermediary fractions to the final freeze drying of final product. Processing techniques include homogenization, standard and continuous-flow centrifugation, ion-exchange chromatography, microfiltration, ultrafiltration, and lyophilization.

EKF Life Sciences fermentation facilities are designed to produce microorganisms, including recombinant organisms, for clinically important enzymes and proteins used in many industrial applications. EKF Life Sciences enzymes are either sold in bulk or used in the production of in vitro diagnostic devices (IVDs). Our experienced team, which has nearly 100 years of working in life sciences, ensures that customers receive a high level of capability and expertise in each and every project.

Contract fermentation

Custom bioprocessing

EKF Life Sciences manufacture enzymes used in clinical diagnostic reagents. These include Arylacylamidase, β-Hydroxybutyrate dehydrogenase, Salicylate hydroxylase and Phenylalanine dehydrogenase. These enzymes are used for the production of Stanbio Chemistry and OEM branded reagents, and are sold commercially to third party clinical diagnostic companies. Other enzymes succesfully produced or in development at EKF Life Sciences include Uricase and ThermoStable Diaphorase.

Arylacylamidase (A-010) Used for the enzymatic determination of acetaminophen in serum

β-Hydroxybutyrate dehydrogenase (H-010) Used for the enzymatic determination of ketone bodies in blood and serum.

Phenylalanine dehydrogenase (P-030) Used for the enzymatic determination of phenylalanine in whole blood or serum

Salicylate hydroxylase (S-010) Used for the enzymatic determination of salicylate in serum.

Diagnostic enzymes